Əsas səhifə

Çap

Əks əlaqə

İnfo
Aspirin in unstable angina

Mündəricat

Aspirin in unstable angina

Sübutlu məlumatların xülasələri
03.10.2017 • Sonuncu dəyişiklik 03.10.2017
Editors

Aspirin alone versus placebo reduces the risk of death, myocardial infarction, and stroke in people with unstable angina.

A topic in Clinical Evidence summarizes the evidence on aspirin in unstable angina pectoris. One systematic review (search date 1990, 145 RCTs, 100000 people) compared antiplatelet treatment versus placebo. Seven of these trials included a total of 4000 people with unstable angina. Antiplatelet treatment (mostly aspirin 75 - 325 mg daily) reduced the combined outcome of vascular death, myocardial infarction, or stroke at 6 months (AR 14% on placebo vs 9% on antiplatelet treatment, RR 0.65, 95% CI 0.51 to 0.79, NNT 20, 95% CI 15 to 34).

Clinical evidence category: Beneficial.

Ədəbiyyat

  1. Natarajan M. Unstable angina. Clin Evid 2002 Jun;(7):214-26.
  2. Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration. BMJ 1994 Jan 8;308(6921):81-106.