A Cochrane review included one study on the efficacy of a single dose of oral indometacin in treating acute postoperative pain in adults, with a total of 59 subjects. Twenty-seven potential papers were identified, but only one small study of women with post-episiotomy pain met the inclusion criteria.
The dose of indometacin assessed against placebo was 50 mg. The number of patients with at least 50% pain relief at 6 hours was 20 out of 29 (69%) for indometacin and 16 out of 30 (53%) for placebo; i.e., there was no significant difference between treatment and placebo (RR 1.3, 95% confidence interval 0.85 to 1.96).