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Gangliosides for acute spinal cord injury

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Gangliosides for acute spinal cord injury

Sübutlu məlumatların xülasələri
02.03.2015 • Sonuncu dəyişiklik 02.03.2015
Editors

Gangliosides may not have any effect on the outcomes of acute spinal cord injury.

A Cochrane review included 2 studies with a total of 797 subjects. There were no deaths in one (n=37). In the other (n=760), there were slightly more deaths in the treatment group than in the control group; odds ratio 1.07 (0.57, 2.00 95%CI) - a result that can be explained by the play of chance. Methodological weaknesses regarding the collection and presentation of data from the two studies made it impossible to reach any conclusions regarding the effect of gangliosides on the other specified outcomes.

Comment: The quality of evidence is downgraded by imprecise results (few patients and wide confidence intervals).

Ədəbiyyat

  1. Chinnock P, Roberts I. Gangliosides for acute spinal cord injury. Cochrane Database Syst Rev 2005 Apr 18;(2):CD004444 [Last assessed as up-to-date: 3 June 2008].