Tazaroten in the treatment of psoriasis
Sübutlu məlumatların xülasələri
27.04.2018 • Sonuncu dəyişiklik 27.04.2018
Editors
Tazarotene appears to be effective in the treatment of psoriasis.
In a randomized controlled double-blind study 324 patients with plaque psoriasis were allocated into three groups: tazarotene gel 0.1%, tazarotene gel 0.05%, and vehicle . The duration of the study was 12 weeks. Both groups on active treatment did better than the vehicle group (p<0.001 with 0.1% gel, and p<0.05 with 0.05% gel).
Comment: The quality of evidence is downgraded by sparse data.
Ədəbiyyat
- Weinstein GD, Krueger GG, Lowe NJ, Duvic M, Friedman DJ, Jegasothy BV, Jorizzo JL, Shmunes E, Tschen EH, Lew-Kaya DA, Lue JC, Sefton J, Gibson JR, Chandraratna RA. Tazarotene gel, a new retinoid, for topical therapy of psoriasis: vehicle-controlled study of safety, efficacy, and duration of therapeutic effect. J Am Acad Dermatol 1997 Jul;37(1):85-92.