Portal vein chemotherapy in colorectal cancer
Sübutlu məlumatların xülasələri
06.08.2013 • Sonuncu dəyişiklik 06.08.2013
Editors
Portal vein infusion of 5-fluorouracil may produce an absolute improvement in 5-year survival of around 5%.
A systematic review included 10 RCTs with a total of 3,499 subjects. Reduction in the annual odds or death was 13.6% (p=0.006), showing cytotoxic 5-fluorouracil-based portal vein infusion to be more effective than no further treatment after surgery. An absolute improvent in survival was 4.7%.
Ədəbiyyat
- Portal vein chemotherapy for colorectal cancer: a meta-analysis of 4000 patients in 10 studies. Liver Infusion Meta-analysis Group. J Natl Cancer Inst 1997 Apr 2;89(7):497-505.