A systematic review was abstracted in DARE. The authors conclude that immunotherapy and intra nasal sodium chromoglycate and beclomethasone should be considered as first line therapy for pregnant women with allergic rhinitis. First generation and second generation antihistamines have not been incriminated as human teratogens. First generation antihistamines are favoured because of longer experience. Oral, intranasal and ophthalmic decongestants should be considered as second line therapy although further studies are needed to clarify their foetal safety.