Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery
Sübutlu məlumatların xülasələri
18.08.2017 • Sonuncu dəyişiklik 18.08.2017
Editors
Prophylactic antibiotics compared to placebo appear to reduce the risk of surgical site infection in patients undergoing breast cancer surgery without reconstruction.
A Cochrane review included 11 trials with a total of 2 867 participants. Prophylactic antibiotics pre-operatively compared to placebo or no antibiotic reduce the incidence of surgical site infection for patients undergoing breast cancer surgery without reconstruction (pooled RR 0.67, 95% CI 0.53 to 0.85; 10 trials, n=2 823). No studies presented separate data for patients who underwent reconstructive surgery at the time of removal of the breast tumour.
Comment: The quality of evidence is downgraded by study quality (inadequate intention-to-treat adherence).
Ədəbiyyat
- Bunn F, Jones DJ, Bell-Syer S. Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery. Cochrane Database Syst Rev 2012;1:CD005360 [Review content assessed as up-to-date: 5 December 2013].