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Probiotics as add-on treatments to corticosteroids for induction of remission in Crohn's disease

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Probiotics as add-on treatments to corticosteroids for induction of remission in Crohn's disease

Sübutlu məlumatların xülasələri
15.07.2017 • Sonuncu dəyişiklik 15.07.2017
Editors

There is insufficient evidence about the efficacy of probiotics for induction of remission in Crohn's disease.

A Cochrane review included 1 study with 11 subjects. There were some methodological concerns with this study; corticosteroids were used concurrently in the two groups. Four of 5 patients in the probiotic group achieved remission compared to 5 of 6 in the placebo group (OR 0.80; 95% CI 0.04 to 17.20).

Comment: The quality of evidence is downgraded by study quality (unclear allocation concealment) and by imprecise results (few patients and wide confidence intervals).

Ədəbiyyat

  1. Butterworth AD, Thomas AG, Akobeng AK. Probiotics for induction of remission in Crohn's disease.Cochrane Database Syst Rev. 2008;(3):CD006634.