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Salicylate for the treatment of Kawasaki disease in children

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Salicylate for the treatment of Kawasaki disease in children

Sübutlu məlumatların xülasələri
02.08.2017 • Sonuncu dəyişiklik 02.08.2017
Editors

Salicylates are probably not effective for the prevention of coronary artery lesions in children with Kawasaki disease.

A Cochrane review included 1 study with a total of 102 subjects. There was no association between the addition of ASA to IVIG treatment on the rate of coronary artery abnormalities at follow up: prior to 30 days from onset of symptoms (RR 0.97; 95% CI 0.43 to 2.19) or at 30 days post onset of symptoms (RR 1.30; 95% CI 0.37 to 4.56).

Comment:The quality of evidence is downgraded by sparse data and poor methodological quality.

Ədəbiyyat

  1. Baumer JH, Love SJ, Gupta A, Haines LC, Maconochie I, Dua JS. Salicylate for the treatment of Kawasaki disease in children. Cochrane Database Syst Rev 2006 Oct 18;(4):CD004175 [Last assessed as up-to-date: 3 February 2009].