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Emergency interventions for hyperkalaemia

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Emergency interventions for hyperkalaemia

Sübutlu məlumatların xülasələri
19.02.2016 • Sonuncu dəyişiklik 19.02.2016
Editors

There is insufficient evidence on the clinical outcomes of emergency interventions for hyperkalemia.

A Cochrane review included 12 studies. None of the studies of clinically-relevant hyperkalaemia reported mortality or cardiac arrhythmias. Reports focussed on serum potassium levels. Many studies were small, and not all intervention groups had sufficient data for meta-analysis to be performed. On the basis of small studies, inhaled beta-agonists, nebulised beta-agonists, and intravenous (IV) insulin-and-glucose were all effective, and the combination of nebulised beta agonists with IV insulin-and-glucose was more effective than either alone. Dialysis is effective. Results were equivocal for IV bicarbonate. K-absorbing resin was not effective by four hours, and longer follow up data on this intervention were not available from RCTs.

Ədəbiyyat

  1. Mahoney BA, Smith WA, Lo DS, Tsoi K, Tonelli M, Clase CM. Emergency interventions for hyperkalaemia. Cochrane Database Syst Rev 2005 Apr 18;(2):CD003235.