Ursodeoxycholic acid and/or antibiotics for prevention of biliary stent occlusion
Sübutlu məlumatların xülasələri
13.07.2017 • Sonuncu dəyişiklik 13.07.2017
Editors
Ursodeoxycholic acid might possibly improve stent patency, but there is insufficient evidence because of sparse data.
A Cochrane review included 5 studies with a total of 258 subjects. Three unblinded trials (n=152) investigating a combination of UDCA and antibiotics versus no treatment did not show a significant treatment effect on the duration of stent patency (hazard ratio (random effects model) 0.58, 95% CI 0.22 to 1.54) or mortality (hazard ratio (fixed effect model) 0.99, 95% CI 0.68 to 1.43). Comment: The quality of evidence was downgraded by sparse data.
Ədəbiyyat
- Galandi D, Schwarzer G, Bassler D, Allgaier HP. Ursodeoxycholic acid and/or antibiotics for prevention of biliary stent occlusion. Cochrane Database Syst Rev 2002;(3):CD003043.