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Reduction versus abrupt cessation in smokers who want to quit

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Reduction versus abrupt cessation in smokers who want to quit

Sübutlu məlumatların xülasələri
21.08.2018 • Sonuncu dəyişiklik 21.08.2018
Editors

Reducing cigarettes smoked before quit day and quitting abruptly appears to be equally effective for smoking cessation.

A Cochrane review included 10 studies with a total of 3760 subjects. Pharmacotherapy was used as part of the interventions in 3 trials. 5 studies included behavioural support in the intervention, 4 included self-help therapy, and the remaining study had arms which included behavioural support and arms which included self-help therapy. 9 studies reported smoking abstinence at either 6 month follow-up, 12 month follow-up, or both, and the remaining trial reported cigarettes per day over seven days at 6, 9, and 12 month follow-ups. Abstinence was verified in 8 studies, by either expired carbon monoxide, saliva cotinine, saliva thiocyanate, or asking a relative or friend to confirm the participant had stopped smoking. Neither reduction or abrupt quitting had superior abstinence rates when all the studies were combined (RR 0.94, 95% CI 0.79 to 1.13), whether pharmacotherapy was used (RR 0.87, 95% CI 0.65 to 1.22), or not (RR 0.97, 95% CI 0.78 to 1.21), whether studies included behavioural support (RR 0.87, 95% CI 0.64 to 1.17) or self-help therapy (RR 0.98, 95% CI 0.78 to1.23).

Comment: The quality of evidence is downgraded by study quality (unclear sequence generation or allocation concealment or incomplete outcome data addressed in half of the studies).

Ədəbiyyat

  1. Lindson N, Aveyard P, Hughes JR. Reduction versus abrupt cessation in smokers who want to quit. Cochrane Database Syst Rev 2010 Mar 17;3:CD008033 [Review content assessed as up-to-date: 19 August 2012].