Conservative management of haemorrhoids in pregnancy and the puerperium

Oral rutosides may relief symptoms from haemorrhoids during pregnancy and puerperium.

A Cochrane review included two studies comparing oral rutosides against placebo, with a total of 150 subjects.

Rutosides seem to be effective in reducing the signs identified by the healthcare provider, and symptoms and signs reported by women, of haemorrhoidal disease. For the outcome no response to treatment: relative risk 0.07, 95% confidence interval 0.03 to 0.20. Regarding perinatal outcomes, one fetal death and one congenital malformation (possible not related to exposure) were reported in the control and treatment group respectively.

Authors' comment: Although the treatment with oral hydroxyethylrutosides looks promising for symptom relief in first and second degree haemorrhoids, its use cannot be recommended until new evidence reassures women and their clinicians about their safety. The review of trials found no studies on, e.g., dietary modifications.

Ədəbiyyat

1. Quijano CE, Abalos E. Conservative management of symptomatic and/or complicated haemorrhoids in pregnancy and the puerperium. Cochrane Database Syst Rev 2005;(3):CD004077 [Review content assessed as up-to-date: 4 May 2010].