NSAIDs for heavy bleeding or pain associated with IUD use
Sübutlu məlumatların xülasələri
13.07.2017 • Sonuncu dəyişiklik 13.07.2017
Editors
Non-steroidal anti-inflammatory drugs are effective compared with placebo in reducing bleeding and pain associated with IUD use.
NSAIDs are recommended over no treatment for heavy menstrual bleeding in patients with IUD and who wish to continue using non-hormone-releasing IUD and do not get sufficient relief from tranexamic acid.
A Cochrane review included 15 trials involving a total of 2 702 women from both developed and developing countries. NSAIDs (naproxen, suprofen, mefenamic acid, ibuprofen, indomethacin, flufenamic acid, alclofenac, and diclofenac) were effective in reducing menstrual blood loss associated with IUD use. This held true for women with and without complaints of heavy bleeding. NSAIDs were effective in reducing pain associated with IUD use. In contrast, prophylactic use of NSAIDs had mixed results; studies with ibuprofen found no
effect on pain after insertion on IUD discontinuation. No important differences emerged in the one trial comparing the effect of different NSAIDs on bleeding.
Ədəbiyyat
- Grimes DA, Hubacher D, Lopez LM, Schulz KF. Non-steroidal anti-inflammatory drugs for heavy bleeding or pain associated with intrauterine-device use. Cochrane Database Syst Rev 2006 Oct 18;(4):CD006034 [Last assessed as up-to-date: 17 August 2011].