A systematic review including 12 studies on troponin T (n=2,847) and 9 studies on troponin I (n=1,901) was abstracted in DARE. For troponin T the cumulative OR for the risk of acute myocardial infarction was 2.7 (95% CI 2.1 to 3.4. The cumulative sensitivity attributable to troponin T for adverse cardiac events was 57% with a cumulative specificity of 68%. For troponin I, the corresponding OR was 4.2 (95% CI 2.7 to 6.4), and the cumulative sensitivity and specificity were 63% and 71%, respectively. In comparative analysis of troponin T vs troponin I, the SROC showed no statistically significant difference between the sensitivity and specificity of troponin T and I.