A systematic review including 10 RCTs with a total of 1,227 subjects was abstracted in DARE. The control treatments included aminoglycoside with clindamycin, third generation cephalosporin with metronidazole, quinolone with metronidazole, and piperacillin with tazobactam. 6 trials reported carbapenem monotherapy to be equivivalent to other antibiotic regimens, 2 trials reported superior outcomes with carbapenem monotherapy, an 2 had outcomes favouring other antibiotic regimens.