A systematic review including 14 studies was abstracted in DARE. Of these 7 assessed the aortoiliac segment, 12 the femoropopliteal segment, and 3 the infragenicular segment.
For the aortoiliac segment, the sensitivity for the detection of greater or equal to 50% stenosis was 80% (95% CI 61% to 93%), and specificity 95% (95% CI 91% to 98%).
For the femoropopliteal segment, the sensitivity for the detection of greater or equal to 50% stenosis was 82% (95% CI 67% to 92%), and specificity 96% (95% CI 93% to 98%).
The sensitivities and specificities for detecting total occlusion in the aortoiliac and femoropopliteal segment were even better than those for the detection of at least 50% stenosis.
For the infragenicular segment, the sensitivity for the detection of occlusion or greater or equal to 50% stenosis was 83% (95% CI 59% to 96%), and specificity 84% (95% CI 69% to 93%).
Comment: The quality of evidence is upgraded by high quality of some original studies and the review.