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Inhaled vs oral steroids for adults with bronchial asthma

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Inhaled vs oral steroids for adults with bronchial asthma

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13.06.2017 • Sonuncu dəyişiklik 13.06.2017
Editors

Inhaled corticosteroids appear to be as effective as a daily dose of 7.5 to 10 mg of prednisolone, probably with fewer adverse effects.

A Cochrane review included 10 small trials. No data could be pooled. Data from six trials produced the same pattern, in which prednisolone 7.5 to 12 mg/day appeared to be as effective as inhaled steroid 300–2000 µg/day. In two trials, inhaled steroids 300–400 µg/day was more effective than prednisolone 5 mg/day. All doses of inhaled corticosteroids appeared to be more effective than alternate day prednisolon up to 60 mg on alternate days.

Comment: The quality of evidence is downgraded by sparse data.

The following decision support rules contain links to this evidence summary:

  • Inhaled corticosteroids instead of oral steroids for chronic asthma

Ədəbiyyat

  1. Mash B, Bheekie A, Jones PW. Inhaled vs oral steroids for adults with chronic asthma. Cochrane Database Syst Rev 2001;(1):CD002160 [Last assessed as up-to-date: 31 July 2008].