A Cochrane review (abstract , review ) included 47 studies with a total of 5 102 subjects. The benefits of vaginal hysterectomy (VH) versus abdominal hysterectomy (AH) were shorter duration of hospital stay (MD 1.1 day, 95% CI 0.9 to 1.2 days; 4 trials, n=295), speedier return to normal activities (MD 9.5 days, 95%CI 6.4 to 12.6 days; 3 RCTs, n=176, statistical heterogeneity I2 = 75%). The benefits of laparoscopic hysterectomy (LH) versus abdominal (AH) were 2=58%) and a smaller drop in haemoglobin level (MD 0.55g/L, 95% CI 0.28 to 0.82g/L), "?>shorter duration of hospital stay (MD 2.6 days, 95% CI 1.1 to 4.1 days; 4 trials, n=466, I2 = 94%), speedier return to normal activities (MD 13.6 days, 95% CI 11.8 to 15.4 days; 6 RCTs, n=520, low quality evidence, at the cot of longer operation timeI2 = 71%)2=96%) "?>, but more urinary tract (bladder or ureter) injuries (OR 2.41, 95% CI 1.2 to 4.8; 13 RCTs, n=2140, I2=0%, low quality evidence). 2=54%) and shorter operation time (MD 25.3 minutes, 95% CI 10.0 to 40.6 minutes). "?>There was no evidence of benefits of laparoscopic versus vaginal hysterectomy (16 RCTs, n=1440). There was a trend of shorter return to normal activites, shorter operation time, and lower costs in the vaginal group compared to the laparoscopic group2=91%) as well as substantial bleeding (OR 2.76, 95% CI 1.02 to 7.42) were increased in LH"?>. For some important outcomes, the analyses were underpowered to detect important differences or they were simply not reported in trials.
Authors' comment: The surgical approach to hysterectomy is best decided by a woman in discussion with her surgeon in light of the relative benefits and hazards.