Low cardiorespiratory fitness and obesity as risk factors for cardiovascular diseases

Low cardiorespiratory fitness may be a strong and independent predictor of CVD and all-cause mortality and comparable in importance with that of diabetes mellitus and other CVD risk factors.

According to a prospective observational study of 25 714 adult men who received medical examination during 1970 to 1993, with mortality follow-up to December 1994, Relative risks for all-cause mortality in obese men ranged from 2.3 (95% CI 1.7 to 2.9) for men with hypertension to 4.7 (95% CI 3.6 to 6.1) for those with cardiovascular disease at baseline. Relative risk for all-cause mortality in obese men with low fitness was 3.1 (95% CI 2.5 to 3.8) and in obese men with diabetes 3.1 (95% CI 2.3 to 4.2). Low fitness was an independent predictor of mortality in all body mass index groups after adjustment for other mortality predictors.

Ədəbiyyat

1. Wei M, Kampert JB, Barlow CE, Nichaman MZ, Gibbons LW, Paffenbarger RS Jr, Blair SN. Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men. JAMA 1999 Oct 27;282(16):1547-53.