Leucocytopenia – Related resources
26.02.2016 • Sonuncu dəyişiklik 03.05.2007
This article is created and updated by the EBMG Editorial Team
Cochrane reviews
- Liposomal amphotericin B appears to be significantly more effective than voriconazole for empirical therapy of suspected fungal infections in neutropenic cancer patients .
- Antibiotic prophylaxis reduces all-cause mortality in afebrile neutropenic patients following chemotherapy. The evidence is strongest for quinolones. The addition of gram-positive prophylaxis reduces the incidence of gram-positive bacteraemia .
- Oral antibiotics are an acceptable alternative to intravenous antibiotics for treating febrile neutropenia in cancer patients at low risk for complications .
- Evidence is inconclusive to support or refute generalised use of granulocyte transfusions to treat infections in patients with neutropenia caused by chemotherapy .
- Empirical anti-Gram-positive antibiotic treatment with glycopeptides (vancomycin, teicoplanin) appears not to improve outcomes in febrile neutropenic cancer patients .
Other evidence summaries
- Imipenem-cilastatin may be more effective than beta-lactam based regimens for empirically treating febrile neutropenic patients .
Other Internet resources
- Distenfeld A. Agranulocytosis. eMedicine
- Godwin JE. Neutropenia. eMedicine
- Neutropenia. Merck Manual Online
- Lymphocytopenia. Merck Manual Online