Pharmacological treatment of cancer pain – Related resources
26.02.2016 • Sonuncu dəyişiklik 17.11.2016
This article is created and updated by the EBMG Editorial Team
Cochrane reviews
- Transdermal fentanyl might possibly be equally effective in reducing cancer pain in comparison to morphine or methadone, with lower rates of constipation.
- Acupuncture might possibly be effective in controlling cancer-related pain in adults, but the evidence is insufficient for conclusions.
- Epidural, subarachnoid, and intracerebroventricular (ICV) administration of opioids all appear to be effective in relieving intractable cancer pain. ICV delivery may be successful if pain is resistant to other treatments .
- Hydromorphone may have similar therapeutic effect and adverse effects to oxycodone and morphine in adults with moderate to severe chronic cancer pain.
- Bisphosphonates appear to give some relief of pain secondary to bone metastases and should be considered when analgesics and/or radiotherapy give inadequate pain relief .
- Oral transmucosal fentanyl citrate is effective in the management of breakthrough pain in patients with cancer .
Other evidence summaries
- Neurolytic coeliac plexus block appears to be effective for pain caused abdominal cancer .
Opioids appear to have no clinically relevant peripheral analgesic efficacy in acute pain .
The benefit of adding codeine to aspirin appears to be small and clinically insignificant .