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Epilepsy in children – Related resources

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Epilepsy in children – Related resources

08.02.2012 • Sonuncu dəyişiklik 26.01.2011
This article is created and updated by the EBMG Editorial Team

Cochrane reviews

  • Education- or counselling-based interventions for children with epilepsy might possibly improve some outcomes relating to epilepsy in children and to the impact that epilepsy can have on parents, although the evidence is insufficient
  • The risk of seizure recurrence appears to be higher with early withdrawal (less than 2 seizure-free years) than with later withdrawal in children .
  • There is insufficient evidence to compare the treatments for infantile spasms .
  • Levetiracetam may reduce seizure frequency when used as an add-on treatment for children with drug-resistant partial epilepsy .
  • Sulthiame might possibly be effective for seizure remission in the short term in children with benign epilepsy with centro temporal spikes, although the evidence is insufficient .
  • Vagal nerve stimulation (VNS) as an add-on treatment is an effective and well tolerated for partial seizures in patients with drug-resistant seizures. VNS stimulation using the high stimulation paradigm is better than low stimulation in reducing frequency of seizures .
  • Carbamazepine may be more effective than phenobarbitone in terms of treatment retention (withdrawals due to lack of efficacy or adverse events or both) .
  • Ketogenic diet might possibly be beneficial for seizure reduction in children and adolescents with epilepsy, even though the adverse effects are frequent. However, the evidence is insufficient .

Other Internet resources

  • Lennox-Gastaut syndrome. Orphanet ORPHA2382

Literature

  • Glauser TA, Cnaan A, Shinnar S, Hirtz DG, Dlugos D, Masur D, Clark PO, Capparelli EV, Adamson PC, Childhood Absence Epilepsy Study Group. Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy. N Engl J Med 2010 Mar 4;362(9):790-9.