Nodular or enlarged thyroid gland – Related resources
08.02.2012 • Sonuncu dəyişiklik 24.08.2007
This article is created and updated by the EBMG Editorial Team
Cochrane reviews
- Iodised salt appears to be an effective means of improving iodine status, but no conclusions can be made about improvements in patient-oriented outcomes, such as physical and mental development in children and mortality .
- Levothyroxine therapy with non-suppressive doses appears to reduce the growth and volume of benign thyroid nodules in euthyroid subjects compared to placebo or no treatment.
Other evidence summaries
- Thyroxine treatment appears to be associated with decreased nodule volume in 17% of patients .
- Subtotal thyroidectomy appears to be the best choice of operation in patients with mild forms of Graves' disease in order to try to achieve a euthyroid state. Total thyroidectomy is probably the best operation for severe disease and large goiter in order to ensure that hyperthyroidism does not recur .
Literature
- Jones MK. Management of nodular thyroid disease. The challenge remains identifying which palpable nodules are malignant. BMJ 2001 Aug 11;323(7308):293-4.