Prevention and screening of colorectal cancer – Related resources
08.02.2012 • Sonuncu dəyişiklik 19.09.2007
This article is created and updated by the EBMG Editorial Team
Cochrane reviews
- Dietary fibre may not be effective in the prevention of colorectal adenomas and carcinomas in the very short term (2 to 4 years follow up) .
- Daily intake of 1 gr dietary calcium may have moderate protective effect on development of colorectal adenomatous polyps .
- Antioxidant supplements have no preventive effect on gastrointestinal cancers. The potential cancer preventive effect of selenium should be studied further .
Other evidence summaries
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The presence of neoplasms in the distal colon appears to increase the risk of advanced neoplasia in the proximal colon, but about 50% of patients with proximal advanced neoplasms have no distal polyps .
- High dietary garlic consumption seems to be associated with decreased risks of laryngeal, gastric, colorectal, and endometrial cancers and adenomatous colorectal polyps but evidence from controlled studies is lacking .
- Colonoscopy may be better than fiberosigmoidoscopy in screening first-degree relatives of patients with colorectal cancer, but there are no studies documenting decreased overall mortality in screened relatives .
The median adherence rate to faecal occult blood screening appears to be 40–50% .
Literature
- Lieberman DA. Clinical practice. Screening for colorectal cancer. N Engl J Med 2009 Sep 17;361(12):1179-87.