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Childhood depression – Related resources

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Childhood depression – Related resources

08.02.2012 • Sonuncu dəyişiklik 25.11.2013
This article is created and updated by the EBMG Editorial Team

Cochrane reviews

  • Antidepressant medication appears to reduce the rate of depression recurrence in children and adolescents .
  • There is insufficient evidence to assess the comparative effectiveness of antidepressive medication, psychological therapies, or a combination of these interventions in the treatment of major depressive disorder in children and adolescents. Antidepressive medication alone may be associated with more suicidal ideations than psychological treatments alone .
  • Targeted and universal depression prevention programmes compared with no intervention may reduce clinically significant depressive episodes in children and adolescents.
  • Antidepressants appear to be more effective than placebo for children and adolescents with best benefits for non-OCD anxiety disorders, intermediate for obsessive-compulsive disorder (OCD) and modest for major depressive disorder (MDD). The benefits appear to be greater than the risk of suicidal ideation/suicide attempt, but the benefit-to-risk ratios vary .

Other evidence summaries

  • Suicide prevention programs seem to be effective in youth at high risk but there is insufficient evidence to either support or not to support curriculum-based suicide prevention programs in schools .