Gestational trophoblastic disease – Related resources
22.07.2013 • Sonuncu dəyişiklik 18.03.2009
This article is created and updated by the EBMG Editorial Team
Cochrane reviews
- Dactinomycin is superior to methotrexate in achieving primary cure without significantly increasing toxicity in low risk gestational trophoplastic neoplasia .
- Prophylactic chemotherapy may reduce the risk of progression to gestational trophoblastic disease in women with complete hydatidiform mole compared with no treatment .
- The combination of methotrexate, actinomycin D and chlorambucil (MAC)might possibly be as effective with less toxicity as the combination of cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, doxorubicin, melphalan and vincristine (CHAMOCA) for high-risk gestational trophoblastic disease, although the data are insufficient.
Literature
Clinical practice reviews
Seckl MJ, Sebire NJ, Berkowitz RS. Gestational trophoblastic disease. Lancet 2010 Aug 28;376(9742):717-29.