Ulcerative colitis – Related resources

Cochrane reviews

• There is insufficient evidence to make conclusions about the efficacy of probiotics compared to mesalazine or placebo for maintenance of remission in ulcerative colitis .
• There is insufficient evidence to make conclusions about the efficacy of probiotics compared to mesalazine or placebo for maintenance of remission in ulcerative colitis .
• Oral budesonide might possibly offer no benefits compared to mesalamine or prednisolone in inducing remission in ulcerative colitis .
• Transdermal nicotine appears to be superior to placebo for the induction of remission in patient's with ulcerative colitis but there is no evidence of any significant advantage compared to standard medical therapy .
• Non-enteric coated omega 3 fatty acids (fish oil) are probably not effective for maintenance of remission in ulcerative colitis .
• Fish oil as an adjunct treatment may be beneficial for induction of remission in ulcerative colitis .
• There is insufficient evidence on the effect of probiotics combined with conventional treatment on induction of remission in ulcerative colitis .
• Low dose methotrexate may not be effective in remission induction in active ulcerative colitis .
• Low dose oral methotrexate may not be effective for maintenance of remission in ulcerative colitis .
• Tacrolimus may be effective for short-term improvement in symptoms in patients with treatment resistant ulcerative colitis at the cost of potential serious side effects. Insufficient treatment and follow-up intervals prevent any conclusions with regard to long-term safety and efficacy .
• MLN-02 may be effective for induction of clinical response and remission in patients with moderately severe ulcerative colitis. Firm conclusions on safety cannot be drawn at this time .
• There may not be differences in mortality or complication rates between open and laparoscopic approach to pouch surgery in patients with ulcerative colitis and familial adenomatous polyposis, but the laparoscopic approach may result in better cosmesis .
• There is insufficient evidence on the impact of specialist nursing interventions on the care and management of patients with inflammatory bowel disease .

Other evidence summaries

• Inflammatory bowel disease patients who receive immunomodulator medications may be at higher risk of lymphoma than the general population. This increased risk could be due to the medication, disease activity, or both .

Other Internet resources

• Ulcerative colitis. Orphanet ORPHA771